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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SVIL All Species: 12.42
Human Site: S575 Identified Species: 45.56
UniProt: O95425 Number Species: 6
    Phosphosite Substitution
    Charge Score: -0.17
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O95425 NP_003165.2 2214 247746 S575 R R E L E L P S S K T E G P Y
Chimpanzee Pan troglodytes XP_001135700 2214 247729 S575 R R E L E L P S S K T E G P Y
Rhesus Macaque Macaca mulatta XP_001083894 2289 256511 S650 R R E L E L P S S K T E G P Y
Dog Lupus familis XP_860137 2279 255498 S641 K Q D P E L Q S S R A E G P P
Cat Felis silvestris
Mouse Mus musculus Q8K4L3 2170 243143 R552 E A S V L D T R V S V A Q L R
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_001030338 1763 198538 G232 S G S A R V P G R E P G M M G
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_784024 1255 142113
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.3 93.8 81.3 N.A. 80.8 N.A. N.A. N.A. N.A. N.A. 47.1 N.A. N.A. N.A. N.A. 28.9
Protein Similarity: 100 99.6 94.7 86.4 N.A. 86.5 N.A. N.A. N.A. N.A. N.A. 60.7 N.A. N.A. N.A. N.A. 39.5
P-Site Identity: 100 100 100 46.6 N.A. 0 N.A. N.A. N.A. N.A. N.A. 6.6 N.A. N.A. N.A. N.A. 0
P-Site Similarity: 100 100 100 73.3 N.A. 6.6 N.A. N.A. N.A. N.A. N.A. 20 N.A. N.A. N.A. N.A. 0
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 15 0 15 0 0 0 0 0 0 15 15 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 15 0 0 15 0 0 0 0 0 0 0 0 0 % D
% Glu: 15 0 43 0 58 0 0 0 0 15 0 58 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 15 0 0 0 0 0 15 0 0 0 15 58 0 15 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 15 0 0 0 0 0 0 0 0 43 0 0 0 0 0 % K
% Leu: 0 0 0 43 15 58 0 0 0 0 0 0 0 15 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 15 15 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 15 0 0 58 0 0 0 15 0 0 58 15 % P
% Gln: 0 15 0 0 0 0 15 0 0 0 0 0 15 0 0 % Q
% Arg: 43 43 0 0 15 0 0 15 15 15 0 0 0 0 15 % R
% Ser: 15 0 29 0 0 0 0 58 58 15 0 0 0 0 0 % S
% Thr: 0 0 0 0 0 0 15 0 0 0 43 0 0 0 0 % T
% Val: 0 0 0 15 0 15 0 0 15 0 15 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 43 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _